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The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.

Horng Ou May, Ap Clodagh O'Shea

Published in Wiley Interdisciplinary Reviews Systems Biology and Medicine

One of the greatest challenges in biomedicine is to define the critical targets and network interactions that are subverted to elicit growth deregulation in human cells. Understanding and developing rational treatments for cancer requires a definition of the key molecular targets and how they interact to elicit the complex growth deregulation pheno...

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