O'Shea Lab - Salk Institute
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Visualizing viral protein structures in cells using genetic probes for correlated light and electron microscopy.

Ou, Horng D Deerinck, Thomas J Bushong, Eric Ellisman, Mark H O'Shea, Clodagh C

Published in Methods (San Diego, Calif.)

Structural studies of viral proteins most often use high-resolution techniques such as X-ray crystallography, nuclear magnetic resonance, single particle negative stain, or cryo-electron microscopy (EM) to reveal atomic interactions of soluble, homogeneous viral proteins or viral protein complexes. Once viral proteins or complexes are separated fro...

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