About the O'Shea Lab
Cellular replication goes awry when something interferes with the normally tight controls on the process, as occurs in both cancer cells and cells infected with DNA viruses, like adenovirus. The Salk Institute research group led by Dr. Clodagh O'Shea is studying the similarities between these two scenarios: understanding how adenovirus uses its own proteins to disrupt control of replication could shed light on what happens when mutations create the same result. It turns out that both systems affect many of the same cellular targets, making adenovirus a very useful tool in the O’Shea lab’s efforts to understand and treat cancer.
For more information on the lab, visit their website: http://oshea.salk.edu/index.php